Identification of phosphorylation sites in keratinocyte transglutaminase
نویسندگان
چکیده
منابع مشابه
Keratinocyte transglutaminase in proliferative vitreoretinopathy.
PURPOSE Proliferative vitreoretinopathy (PVR) is an excessive wound-healing process and the major complication in rhegmatogenous retinal detachment. The present study was designed to investigate the expression of keratinocyte transglutaminase (kTgase) in PVR membranes and retinal pigment epithelial (RPE) cells and to evaluate its expression in response to growth factors known to be increased in...
متن کاملPrimary structure of keratinocyte transglutaminase.
The nucleotide and deduced amino acid sequences of the coding regions of human and rat keratinocyte transglutaminases (protein-glutamine: amine gamma-glutamyltransferase; EC 2.3.2.13) have been determined. These yield proteins of approximately 90 kDa that are 92% identical, indicative of the conservation of important structural features. Alignments of amino acid sequences show substantial simil...
متن کاملIdentification of phosphorylation sites in GIT1.
G protein-coupled receptor kinaseinteracting protein 1 (GIT1) was originally identified as an ADP ribosylation factor GTPase-activating protein (ARF-GAP) that binds Gprotein-coupled receptor kinases (GRKs) and regulates membrane trafficking (Premont et al., 1998). Subsequent studies have shown a much broader function for GIT1 and GIT2/PKL as regulators of migrationrelated processes, including a...
متن کاملIdentification of phosphorylation sites in PIX and PAK1
phosphorylation sites in PIX and PAK1 Mark W. Mayhew1, Erin D. Jeffery2, Nicholas E. Sherman3, Kristina Nelson3, Joy M. Polefrone2, Stephen J. Pratt1, Jeffrey Shabanowitz2, J. Thomas Parsons4, Jay W. Fox2, Donald F. Hunt2,5 and Alan F. Horwitz1,* Departments of 1Cell Biology, 2Chemistry, 3W. M. Keck Biomedical Mass Spectrometry Laboratory, 4Microbiology, and 5Pathology, University of Virginia, ...
متن کاملComprehensive identification of phosphorylation sites in postsynaptic density preparations.
In the mammalian central nervous system, the structure known as the postsynaptic density (PSD) is a dense complex of proteins whose function is to detect and respond to neurotransmitter released from presynaptic axon terminals. Regulation of protein phosphorylation in this molecular machinery is critical to the activity of its components, which include neurotransmitter receptors, kinases/phosph...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1996
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj3200547